KCNJ13

KCNJ13
Identifiers
Aliases	KCNJ13, KIR1.4, KIR7.1, LCA16, SVD, potassium voltage-gated channel subfamily J member 13, potassium inwardly rectifying channel subfamily J member 13
External IDs	OMIM: 603208; MGI: 3781032; HomoloGene: 55638; GeneCards: KCNJ13; OMA:KCNJ13 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)[1]
End	232,776,565 bp[1]
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)[2]
End	87,322,451 bp[2]
RNA expression pattern
	Top expressed in
	Epithelium of choroid plexus; ; retinal pigment epithelium; ; jejunal mucosa; ; testicle; ; buccal mucosa cell; ; sural nerve; ; mucosa of ileum; ; Achilles tendon; ; duodenum; ; bone marrow cell;
	Top expressed in
	Epithelium of choroid plexus; ; retinal pigment epithelium; ; iris; ; otolith organ; ; utricle; ; ciliary body; ; sciatic nerve; ; olfactory epithelium; ; stria vascularis; ; vestibular membrane of cochlear duct;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	inward rectifier potassium channel activity; voltage-gated ion channel activity;
Cellular component	integral component of membrane; integral component of plasma membrane; membrane;
Biological process	potassium ion transport; regulation of ion transmembrane transport; ion transport; potassium ion import across plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	3769
	100040591
	ENSG00000115474
	ENSMUSG00000079436
	O60928
	P86046
	NM_002242; NM_001172416; NM_001172417
	NM_001110227
	NP_001165887; NP_001165888; NP_002233
	NP_001103697
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium inwardly-rectifying channel, subfamily J, member 13 (KCNJ13) is a human gene encoding the Kir7.1 protein.[5]

References

^ a b c GRCh38: Ensembl release 89: ENSG00000115474 – Ensembl, May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000079436 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: KCNJ13 potassium inwardly-rectifying channel, subfamily J, member 13".

Kubo Y, Adelman JP, Clapham DE, Jan LY, Karschin A, Kurachi Y, Lazdunski M, Nichols CG, Seino S, Vandenberg CA (December 2005). "International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels". Pharmacological Reviews. 57 (4): 509–26. doi:10.1124/pr.57.4.11. PMID 16382105. S2CID 11588492.
Krapivinsky G, Medina I, Eng L, Krapivinsky L, Yang Y, Clapham DE (May 1998). "A novel inward rectifier K+ channel with unique pore properties". Neuron. 20 (5): 995–1005. doi:10.1016/S0896-6273(00)80480-8. PMID 9620703. S2CID 16356235.
Partiseti M, Collura V, Agnel M, Culouscou JM, Graham D (August 1998). "Cloning and characterization of a novel human inwardly rectifying potassium channel predominantly expressed in small intestine". FEBS Letters. 434 (1–2): 171–6. Bibcode:1998FEBSL.434..171P. doi:10.1016/S0014-5793(98)00972-7. PMID 9738472. S2CID 27138272.
Döring F, Derst C, Wischmeyer E, Karschin C, Schneggenburger R, Daut J, Karschin A (November 1998). "The epithelial inward rectifier channel Kir7.1 displays unusual K+ permeation properties". The Journal of Neuroscience. 18 (21): 8625–36. doi:10.1523/JNEUROSCI.18-21-08625.1998. PMC 6793533. PMID 9786970.
Derst C, Döring F, Preisig-Müller R, Daut J, Karschin A, Jeck N, Weber S, Engel H, Grzeschik KH (December 1998). "Partial gene structure and assignment to chromosome 2q37 of the human inwardly rectifying K+ channel (Kir7.1) gene (KCNJ13)". Genomics. 54 (3): 560–3. doi:10.1006/geno.1998.5598. PMID 9878260.
Nakamura N, Suzuki Y, Sakuta H, Ookata K, Kawahara K, Hirose S (September 1999). "Inwardly rectifying K+ channel Kir7.1 is highly expressed in thyroid follicular cells, intestinal epithelial cells and choroid plexus epithelial cells: implication for a functional coupling with Na+,K+-ATPase". The Biochemical Journal. 342 ( Pt 2) (2): 329–36. doi:10.1042/0264-6021:3420329. PMC 1220469. PMID 10455019.
Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S (January 2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.

External links

KCNJ13+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000115474 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000079436 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: KCNJ13 potassium inwardly-rectifying channel, subfamily J, member 13".

KCNJ13

See also

References

Further reading

External links